Record Dengue Surge in the United States in 2024 Fueled by Travel-Associated Cases

CDC data show a record 3,798 dengue cases in the United States and DC in 2024, up 359% from the 2010–2023 average, with travel-associated cases (97.2%) far exceeding locally acquired ones (2.8%). The Caribbean, Mexico, and Cuba were major exposure regions; Florida, California, and Texas reported local transmission in multiple counties. The median patient age was 49; 57.5% identified as Hispanic/Latino, and 36.1% were hospitalized, with six deaths (0.2%). DENV-3 was the most common serotype among those tested. The findings call for stronger prevention, vector control, and traveler-focused messaging, while vaccines are not yet available for short-term travelers; protective measures include EPA-approved repellents, protective clothing, screens, and reducing standing water.