Tesla short sellers suffer significant losses in 2021.

Tesla short sellers have lost $5.52 billion in the year to date, despite a profitable April, according to financial analytics firm S3 Partners. Tesla is the second most shorted US stock after Apple, with short interest around $15.42 billion. Since Tesla began trading in 2010, short sellers have lost $55.4 billion in mark-to-market losses. Tesla is scheduled to report its first-quarter earnings later on Wednesday, which could add to short sellers' losses in the longer term.