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ImmunityBio's NAI+BCG Delivers More Durable Complete Responses in BCG-Unresponsive NMIBC at AUA 2026
business54 minutes ago

ImmunityBio's NAI+BCG Delivers More Durable Complete Responses in BCG-Unresponsive NMIBC at AUA 2026

ImmunityBio presented indirect treatment comparison analyses at AUA 2026 showing nogapendekin alfa inbakicept-pmln (NAI) plus BCG achieving higher and longer-lasting complete responses than nadofaragene firadenovec-vncg in BCG-unresponsive NMIBC with CIS (anytime CR 69.7% vs 53.4%; median CR duration 22.1 vs 9.7 months; cystectomy-free HR 0.40). In comparison with TAR-200, NAI+BCG had a higher 12‑month CR (49.2% vs 45.9%) and substantially fewer treatment-related adverse events (61.7% vs 83.5%) based on MAIC analyses. Results are from unanchored indirect comparisons and should be interpreted with caution, but support IL-15–driven, bladder-sparing immunotherapy potential in NMIBC with CIS. The company also cites ongoing BCG development efforts, including Tokyo strain and recombinant BCG programs.

Radar crosses unicorn threshold with $170M Series B for RFID-driven retail inventory
business1 hour ago

Radar crosses unicorn threshold with $170M Series B for RFID-driven retail inventory

Radar, a RFID-based retail inventory startup backed by Jay Schottenstein, raised $170 million in a Series B led by Gideon Strategic Partners and Nimble Partners, valuing the company above $1 billion and expanding its deployments with retailers like American Eagle and Old Navy. The platform provides real-time in-store inventory visibility to reduce shrink and improve product availability, with reported gains in stock accuracy and lower order cancellation rates for buy-online-pickup-in-store.

UK petrol spikes to wartime high as Iran conflict pushes oil costs
business1 hour ago

UK petrol spikes to wartime high as Iran conflict pushes oil costs

UK unleaded petrol jumped to 158.52p per litre — the highest since the start of the Iran war — as Brent crude climbed to around $111 a barrel from about $73 pre-conflict, lifting pump prices; diesel rose to 185.92p. The RAC says petrol could push past 160p unless oil prices ease, while diesel looks relatively more positive. The chancellor’s plans to raise fuel duty are under review, but the Treasury did not comment.

Mango founder’s son detained in renewed probe into fatal Montserrat fall
business1 hour ago

Mango founder’s son detained in renewed probe into fatal Montserrat fall

Jonathan Andic, 43, son of Mango founder Isak Andic, has been arrested by Catalan police as part of a renewed inquiry into his father’s December 2024 death after a fall from a cliff in the Montserrat mountains; investigators say inconsistencies in his testimony led to reopening the case, though the family denies any involvement and he was to be questioned again before a judge.

Microsoft unveils Intel-powered Surface Pro 12 and Laptop 8 for business
gadgets2 hours ago

Microsoft unveils Intel-powered Surface Pro 12 and Laptop 8 for business

Microsoft has unveiled three Intel-powered Surface devices for business: the Surface Pro 12 and Surface Laptop 8, plus a 13-inch Surface Laptop for Business edition. Base pricing starts around $1,949.99, with higher-end Pro 12 configurations reaching up to $4,399.99 (OLED and 5G options available); the 13.8-inch Laptop 8 starts at $1,949.99 and adds a privacy screen option, while the 15-inch variant gains a higher-resolution 3270x2180 panel at 120Hz. All models keep Surface Connect charging and USB-C/Thunderbolt 4 ports, and the Laptop 8 adds an advanced haptic touchpad, signaling premium enterprise pricing ahead of potential consumer models later this year.

Starbucks Korea sacks CEO after Tank Day promo tied to Gwangju crackdown
business2 hours ago

Starbucks Korea sacks CEO after Tank Day promo tied to Gwangju crackdown

Starbucks Korea fired its CEO after a tank-themed tumbler promo timed to Democratisation Movement Day drew backlash for echoing the 1980s crackdown on pro-democracy protesters. The campaign was withdrawn, leaders apologized, and Starbucks Global said a thorough internal investigation and stronger controls would follow; Shinsegae Group also apologized as the stock moved lower, underscoring questions about marketing sensitivity and corporate accountability.

Home Depot: Modest Q1 FY2026 Growth, Guidance Reaffirmed
business3 hours ago

Home Depot: Modest Q1 FY2026 Growth, Guidance Reaffirmed

The Home Depot reported Q1 FY2026 sales of $41.8 billion (up 4.8% YoY) with 0.6% comparable sales growth; net earnings were $3.29 billion and adjusted EPS $3.43. It reaffirmed fiscal 2026 guidance: about 2.5%–4.5% sales growth, comparable sales roughly flat to +2%, gross margin ~33.1%, operating margin 12.4%–12.6%, and adjusted EPS up about flat to 4% from 2025, with capex ~2.5% of sales and ~15 new stores. The results reflect steady demand amid housing affordability pressures, as the company continues to operate ~2,361 stores and over 1,280 SRS locations with roughly 470,000 associates.

Treasury yields ease as traders eye 30-year near-1999 highs
business3 hours ago

Treasury yields ease as traders eye 30-year near-1999 highs

U.S. Treasuries pulled back slightly after Monday’s spike, with the 10-year yield around 4.62% and the 30-year near 5.14%, while the 2-year sits near 4.08%. A Bank of America survey shows 62% of global fund managers expect 30-year yields to reach 6%—the highest since 1999—helped by ongoing inflation pressures from energy costs and deficits; analysts caution that the market’s rate-hike expectations may be excessive if inflation and growth dynamics diverge. Oil prices remain elevated, underscoring long-end pressure.

Next-gen obesity drug race tightens as pivotal readouts loom
business3 hours ago

Next-gen obesity drug race tightens as pivotal readouts loom

Pharma is racing to commercialize next-generation obesity drugs as pivotal readouts approach from Lilly, Viking Therapeutics, and Pfizer; Lilly’s retatrutide shows potentially stronger weight loss and knee-pain relief in Triumph-4, Viking is testing maintenance dosing for VK2735, and Pfizer’s PF’3944 posted encouraging phase 2b results for monthly maintenance injections, signaling a crowded path to a multi-billion GLP-1 market by 2030.

Cannes 2026: Indie Deals Rewire Finance and Distribution
business3 hours ago

Cannes 2026: Indie Deals Rewire Finance and Distribution

At Cannes 2026, a handful of high-profile sales (A24’s eight-figure world rights for Club Kid and Amazon’s eight-figure package for Pumping Black) contrasted with a broader slow market, underscoring a shift away from the traditional pay-one window. Independent distributors are increasingly relying on equity financing, niche audiences, and direct-to-fan approaches—exemplified by Watermelon Pictures and Angel Studios—while re-releases (like Pan’s Labyrinth and The Devils) hint at a blended theatrical future. In short, dealmaking has not vanished but is being reinvented around community-driven distribution and new revenue paths, with much of the market activity likely to close after Cannes as buyers digest risk and value.

Home Depot rides resilient demand in Q1 2026, sticks to full-year outlook
business5 hours ago

Home Depot rides resilient demand in Q1 2026, sticks to full-year outlook

Home Depot beat expectations in Q1 2026 with adjusted EPS of $3.43 on $41.77 billion in revenue and reaffirmed its full-year guidance of 2.5%–4.5% sales growth (up to 4% adjusted EPS growth). Net income was $3.29 billion GAAP, or $3.30 per share. The company notes core homeowners remain engaged but are deferring larger projects amid higher gas prices and weaker housing conditions, while expanding its pro-focused business—backed by acquisitions of SRS Distribution, GMS, and Mingledorff’s—to capture a roughly $700 billion pro market.

StanChart charts leaner path: 15% corporate-role cut by 2030 to lift returns
business7 hours ago

StanChart charts leaner path: 15% corporate-role cut by 2030 to lift returns

Standard Chartered will cut more than 15% of its corporate-function roles by 2030 to lift income per employee about 20% by 2028 and target ROE of ~15% in 2028 and ~18% in 2030. Of ~82,000 employees, about 52,000 work in support roles. CEO Bill Winters says the move funds sustainable growth and higher-quality returns; Jefferies calls the targets conservative. The bank recently posted a 17% profit rise but took a $190 million charge tied to Middle East conflict and is expanding Middle East trade, along with a new $300 million IFC-backed risk-sharing facility to bolster Africa’s supply chains.

LIRR strike ends as unions reach tentative wage deal
business7 hours ago

LIRR strike ends as unions reach tentative wage deal

A three-day strike by workers on the Long Island Rail Road, the nation’s largest commuter railroad, ended with a tentative wage deal between unions and the MTA. The agreement includes raises without any additional fare increases and must be ratified by the five unions; roughly 3,500 workers are set to return to work as service resumes in phases. The LIRR’s ridership remains well below pre‑pandemic levels, and fares for the strike period will be prorated or refunded where applicable.

AI-driven overhaul prompts Standard Chartered to trim nearly 8,000 jobs
business7 hours ago

AI-driven overhaul prompts Standard Chartered to trim nearly 8,000 jobs

Standard Chartered plans to cut almost 8,000 jobs—more than 15% of its back-office staff by 2030—as it places AI at the center of a new growth strategy, describing the move as replacing lower-value human work with capital and training to redeploy staff, while targeting higher returns, more income per employee, and a larger dividend, alongside leadership changes and investor-day highlights.