Oropouche Virus Infections May Reach 9.4 Million Across Latin America, Study Finds

Two new studies estimate the Oropouche virus has infected about 9.4 million people across Latin America and the Caribbean since 1960, far exceeding reported cases due to many mild or asymptomatic infections and rural transmission; Manaus shows high seroprevalence, and researchers urge decentralized, integrated serological, environmental, and genomic surveillance to guide prevention and vaccination as a possible new viral lineage evolves.