Large brain-imaging review ties regular cannabis use to brain function changes

A brain-imaging analysis of hundreds of thousands of scans links habitual cannabis use with widespread reductions in cerebral blood flow in regions tied to memory, coordination, emotion and executive function. THC appears to disrupt the cerebellum and hippocampus, potentially impairing memory formation and judgment, with effects strongest in the hour after use; research suggests some brain changes may ease after quitting, but long‑term impacts on memory and mental health remain a concern and are still being studied.