Persistent Long-COVID Symptoms Persist in Half of Patients After 18 Months

A study based on cases seen at a Danish post-COVID clinic found that over 50% of long-COVID patients failed to improve 1.5 years after their initial diagnosis, regardless of the variant they were infected with. The study included 806 patients infected with the wild-type strain, Alpha, Delta, or Omicron. Patients infected in the Delta period initially had more severe long-COVID symptoms, while patients infected with Omicron had a lower health-related quality of life compared to those infected with the wild-type strain. Overall, patients had no clinically meaningful decline in the severity of long-COVID after 1.5 years.