Tag

Long Covid

All articles tagged with #long covid

Severe COVID may awaken dormant viruses, fueling long-COVID questions
health1 day ago

Severe COVID may awaken dormant viruses, fueling long-COVID questions

A study of 1,154 adults hospitalized with COVID-19 found that severe infection can reactivate dormant viruses in the body, including EBV, CMV, HSV and anelloviruses. Nearly half (about 550 participants) showed at least one reactivation, with different viruses turning on at different times and linking to immune/metabolic changes and persistent long-COVID symptoms in some patients. While these findings suggest a potential role for viral reactivation in disease severity and long COVID, the authors stress that RNA detection shows association, not causation, and call for prospective interventional trials to test whether antiviral treatment could improve outcomes.

Dormant viruses awaken during COVID-19, potentially driving severity and long COVID
health1 day ago

Dormant viruses awaken during COVID-19, potentially driving severity and long COVID

A study of 1,150 hospitalized COVID-19 patients found reactivation of dormant viruses from the Herpesviridae and Anelloviridae families in about 48% of cases, with HSV1 and CMV reactivating around day 20 and detection in nasal or blood samples linked to greater disease severity and higher 1-year mortality. Notably, Anelloviridae reactivation months after illness was associated with fatigue and disability (long COVID). The study shows association, not causation, and involved unvaccinated patients with early SARS-CoV-2 strains, so more research is needed to understand implications for prognosis and treatment."

Dormant viruses wake up in COVID-19 patients, impacting severity and long COVID
health1 day ago

Dormant viruses wake up in COVID-19 patients, impacting severity and long COVID

A year-long study of over 1,150 hospitalized, unvaccinated COVID-19 patients found that about 48% experienced reactivation of dormant viruses, notably Epstein-Barr virus and cytomegalovirus, with reactivations linked to greater acute severity and higher 1-year mortality in the critically ill; reactivation of Anelloviridae during recovery was associated with long COVID fatigue and disability. The study does not prove causation and has limitations (older SARS-CoV-2 strains, no vaccination status, sampling constraints), but suggests viral reactivation could influence COVID-19 outcomes and may inform risk assessment and future therapies pending further research.

Shingles vaccine eases acute pain and cuts long-term risk, with guidance for long COVID care
health7 days ago

Shingles vaccine eases acute pain and cuts long-term risk, with guidance for long COVID care

Shingles can occur even after vaccination, but the shot lowers the severity and duration of acute pain, reduces pain medication use, and, by about 90%, lowers the risk of lingering postherpetic neuralgia. Start antiviral treatment (e.g., valacyclovir) within 24–72 hours of rash onset, and see an ophthalmologist promptly for shingles near the eye. Adults over 50 should get the shingles vaccine unless contraindicated. For long COVID, a COVID vaccine is safe and can prevent future long COVID; recovery is gradual and aided by tailored exercise, good sleep, stress management, and possibly probiotics, with no single magic cure.

MRI reveals enduring brain changes in both long COVID patients and recovered individuals
science9 days ago

MRI reveals enduring brain changes in both long COVID patients and recovered individuals

A small multimodal MRI study (47 adults) found lasting brain tissue and neurochemical changes in people with long COVID and those who recovered, compared with never-infected controls. Using myelin-sensitive imaging, diffusion MRI, and MR spectroscopy, researchers observed elevated myelin signals in several regions for both groups, with distinct patterns (higher signals in brainstem and cerebellum for the recovered group; higher signals in the precentral gyrus and middle temporal gyrus for long COVID). Diffusion reductions were noted in various regions, and neurochemical shifts differed (long COVID: higher N-acetyl-aspartate; recovered: higher glutamine). Some myelin measures correlated with physical and cognitive impairment. However, the study is small and cross-sectional, so it cannot establish causality or track changes over time; larger longitudinal work is needed to determine whether these changes are permanent or reversible.

Severe COVID-19 May Wake Hidden Viruses, Study Shows
science13 days ago

Severe COVID-19 May Wake Hidden Viruses, Study Shows

A Nature study of 1,154 hospitalized COVID-19 patients across the U.S. and Canada found 11 dormant viruses reactivated within 40 days of admission, including herpes viruses (Epstein–Barr virus, cytomegalovirus) and Anelloviridae; reactivation appeared linked to inflammation and severe illness, with Anelloviridae reactivation associated with long‑term disability and long COVID, though causality is not proven. The findings may inform future diagnostics and treatments, but applicability to milder cases remains uncertain.

Dormant viruses wake in severe COVID-19 patients, new study suggests
health15 days ago

Dormant viruses wake in severe COVID-19 patients, new study suggests

A large multi-center study of 1,154 hospitalized COVID-19 patients found 11 dormant viruses reactivated within 40 days of admission, including Epstein-Barr, cytomegalovirus, herpes simplex virus-1 and Anelloviridae; Anelloviridae reactivation was linked to long COVID and disability, while EBV/CMV reactivation appeared tied to inflammation rather than immune suppression. The study does not prove causation but may help explain long COVID and guide future diagnostics and therapies, though results apply to severe cases only.

Long COVID Linked to 18% Drop in Brain Dopamine Nerve Endings, PET Study Finds
health16 days ago

Long COVID Linked to 18% Drop in Brain Dopamine Nerve Endings, PET Study Finds

A small PET study (24 long COVID patients and 24 controls) found about an 18% reduction in dopamine nerve endings in the striatum of people with long COVID, with ventral striatum changes linked to lower motivation and dorsal striatum changes tied to slower movement and memory issues. The alterations persisted for up to 4.6 years after infection, suggesting the dopaminergic system as a potential biomarker for diagnosis and a target for treatment. The study’s sample is small, but researchers plan a clinical trial repurposing a dopamine-influencing drug, highlighting the need for validated long COVID therapies and better access to care.

Today’s Everyday Things, Tomorrow’s Health Hazards: Readers Predict the Next Asbestos
science17 days ago

Today’s Everyday Things, Tomorrow’s Health Hazards: Readers Predict the Next Asbestos

A BuzzFeed Community post collects readers’ predictions about which everyday items and habits could be proven harmful in the future, ranging from microplastics and PFAS to AI-driven social media, scented products, vaping, and long-term effects of COVID, highlighting concerns about environmental exposures, consumer goods, and modern lifestyles becoming health risks down the line.

Dormant viruses reawaken in severe COVID, fueling long COVID and autoimmune risks
health19 days ago

Dormant viruses reawaken in severe COVID, fueling long COVID and autoimmune risks

Nature study of 1,154 hospitalized COVID-19 patients shows severe illness can reactivate dormant viruses (11 viruses detected within 40 days), notably Anelloviridae linked to long COVID, while EBV and CMV reactivation in nasal/blood samples correlate with higher mortality and complications; findings suggest viral reactivation monitoring could help prognosticate and treat acute and long COVID, though causality isn’t proven and more research is planned.

Chronic Virus Reactivation Linked to Severity and Long COVID in COVID-19 Patients
science20 days ago

Chronic Virus Reactivation Linked to Severity and Long COVID in COVID-19 Patients

A large, longitudinal study of 1,154 hospitalized COVID-19 patients using multi-omic analyses found significant reactivation of chronic viruses, especially Herpesviridae (EBV, CMV, HSV) and Anelloviridae, during acute illness with distinct timing for different viruses. Reactivation correlated with greater disease severity and adverse outcomes and persisted into convalescence, with Anelloviridae associated with long COVID. Although causality isn’t established, the results show frequent viral reactivation in immunocompetent patients during severe illness and reveal immune, transcriptomic, and metabolic changes linked to reactivation, offering potential prognostic and therapeutic insights for acute COVID-19 and long COVID.

Vaccines Still Protect Against Severe Covid-19 as Masking and Immunity Debates Evolve
health22 days ago

Vaccines Still Protect Against Severe Covid-19 as Masking and Immunity Debates Evolve

Vaccines continue to provide strong protection against severe illness and death from Covid-19, with ongoing safety monitoring; masking guidance has evolved as we learned more about transmission; herd immunity for Covid proved fragile and not a simple goal; the US faced heavy hospital strain and a high death toll, while long Covid affects millions, all amid politicized public discourse and misinformation.

Long COVID linked to dopamine nerve loss in the brain
science26 days ago

Long COVID linked to dopamine nerve loss in the brain

A new eBioMedicine study finds long COVID patients show an average 18% reduction in dopamine-releasing nerve terminals in the striatum, measured by VMAT2 binding, with lower dopamine cell density correlating with apathy, slower motor speed, and memory issues; blood biomarkers did not reflect these brain changes. The authors suggest dopamine-enhancing treatments could help some patients, but note the study’s small, associative design and call for larger, longitudinal research to confirm causality and guide therapy.