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Long Covid

All articles tagged with #long covid

Eye symptoms flag tougher long COVID, Yale study finds
health2 days ago

Eye symptoms flag tougher long COVID, Yale study finds

A Yale-led study of 595 adults with long COVID found that new eye symptoms after infection (blurred vision, dry eyes, floaters) are linked to a more severe disease profile, including worse overall health, higher autonomic symptoms (POTS, dizziness, tremors), more GI issues and migraines, and greater financial/housing instability; authors say ocular symptoms may indicate more-severe long COVID and call for more research, though limitations include self-reported data and a predominantly female/White sample.

New Monocyte State Tied to Long COVID Fatigue and Breathing Issues
health-and-medicine12 days ago

New Monocyte State Tied to Long COVID Fatigue and Breathing Issues

A single-cell multiomics study of Long COVID patients found a distinct molecular state in CD14+ monocytes (LC-Mo), especially common in those who had mild-to-moderate initial infection. LC-Mo correlates with fatigue and respiratory symptoms and is linked to elevated cytokine levels, offering a new lead for personalized treatment and deeper understanding of Long COVID.

Repeated COVID Infections Pose Greater Health Risks, Experts Warn
health16 days ago

Repeated COVID Infections Pose Greater Health Risks, Experts Warn

Doctors warn that catching COVID again isn’t harmless: reinfections are linked to a higher risk of long COVID and chronic conditions like diabetes or kidney disease, with CDC data showing substantial hospitalizations and deaths in the latest year. The best defense is staying up to date with annual vaccines, which reduce the risk of severe disease and long COVID, though there is currently no cure for long COVID. Management focuses on symptoms and quality-of-life improvements through rehab, sleep and mental health support; if you suspect long COVID, consult your healthcare provider.

Long COVID lingers in Swiss healthcare workers four years after infection
health21 days ago

Long COVID lingers in Swiss healthcare workers four years after infection

A Swiss multicenter study of healthcare workers followed for up to four years after infection with ancestral SARS‑CoV‑2 found that up to 60% still reported at least one symptom four years later; fatigue, loss of smell/taste, and brain fog were most common, and while most symptoms waned over time, a substantial minority continued to experience long COVID, highlighting the need for long‑term clinical and occupational support.

Vitamin D Fails to Ease COVID, but May Lower Long COVID Risk in Adherent Users
health-and-medicine27 days ago

Vitamin D Fails to Ease COVID, but May Lower Long COVID Risk in Adherent Users

In the VIVID randomized trial, Mass General Brigham researchers found that high-dose vitamin D3 did not reduce COVID-19 severity, hospitalizations, or transmission. However, among participants who consistently followed the supplementation regimen, there was a borderline-significant hint that long COVID symptoms eight weeks after infection were less common (21% vs 25% in the placebo group), meriting further study. The trial enrolled 1,747 COVID-positive adults and 277 household contacts across the U.S. and Mongolia, using a regimen of 9,600 IU/day for two days then 3,200 IU/day for four weeks, starting about three days after a positive test. The study, published in The Journal of Nutrition, emphasizes no clear acute benefits but suggests a potential long-COVID effect in adherent users.

Vitamin D High Doses Do Not Cut Acute COVID Risk, But May Hint at Long COVID Benefit
health29 days ago

Vitamin D High Doses Do Not Cut Acute COVID Risk, But May Hint at Long COVID Benefit

A large randomized trial (VIVID) found that high-dose vitamin D3 did not reduce short-term COVID-19 severity, hospitalizations, or transmission. However, among participants who consistently took the supplement, there was a borderline-significant reduction in long COVID symptoms at eight weeks (21% vs 25%), suggesting a possible benefit that warrants further study.

Taste Buds Reveal Why Some Post-COVID Flavors Stay Gone
health1 month ago

Taste Buds Reveal Why Some Post-COVID Flavors Stay Gone

A study in Chemical Senses followed 28 adults with lasting post-COVID taste changes, finding both weakened molecular signaling in taste cells and structural anomalies in taste buds; eight participants had clearly abnormal taste scores, with sweet, bitter, and umami most affected while salty and sour were largely preserved. Biopsies showed disorganized taste buds and atypical taste cells, though no SARS-CoV-2 genetic material was detected in the tissue, suggesting the virus doesn't linger there. The researchers propose that initial infection-triggered inflammation or nerve signaling disruption may underlie persistent taste loss, which can persist even as taste buds regenerate, highlighting cellular targets for future treatments.

Flu Outpaces COVID This Winter, Vaccines Still the Frontline Defense
health1 month ago

Flu Outpaces COVID This Winter, Vaccines Still the Frontline Defense

Flu has surged this season while COVID-19 remains present but generally milder; the CDC estimates about 25 million flu infections, 330,000 hospitalizations, and 20,000 deaths, versus 3–9 million COVID illnesses, 96,000–170,000 hospitalizations, and 10,000–30,000 deaths. Vaccines and prior immunity are blunting severe outcomes for both, but flu’s circulating H3N2 mutation and uneven vaccination uptake keep the outlook uncertain, and studies suggest COVID-19’s acute impact may be waning even as questions about long-term effects and coinfections linger.

Mild COVID-19 May Leave Lasting Brain Changes, Tulane Study Finds
health1 month ago

Mild COVID-19 May Leave Lasting Brain Changes, Tulane Study Finds

A Tulane study using a mouse model found that while both COVID-19 and influenza can cause lasting lung injury, only SARS-CoV-2 infection led to persistent brain inflammation and microvascular damage after the virus was no longer detectable, helping explain long-COVID brain symptoms and highlighting distinct brain-attack mechanisms from flu; findings could inform post-infection monitoring and treatment.

Long COVID Persists in Millions Despite Declining Rates
health1 month ago

Long COVID Persists in Millions Despite Declining Rates

A Yale-led study using NHIS data estimates that by 2024 about 8.3% of U.S. adults (roughly 21 million) had ever had long covid, with around 60% reporting recovery. The risk of developing long covid declined over the pandemic (from ~19.7% to 13.7%), while recovery rates rose (from ~51.2% to 59.7%), though self-reported data and the lack of a proven treatment introduce limitations. Findings align with NIH RECOVER and indicate millions remain affected and in need of understanding and care.

Long COVID: Eight Forms Identified, Treatments Lag
health1 month ago

Long COVID: Eight Forms Identified, Treatments Lag

A physician watches his 28-year-old daughter, Samantha, endure severe long COVID, a condition now recognized to have eight distinct forms; despite growing scientific awareness, effective treatments remain scarce, forcing patients to carefully budget energy, endure debilitating “crashes” that can confine them to bed for days, and rely on disciplined routines as researchers seek better therapies.

Diving Into Long Covid: One Woman’s Quest to Stay Afloat
health1 month ago

Diving Into Long Covid: One Woman’s Quest to Stay Afloat

A 34-year-old writer recounts living with long Covid—enduring fatigue, nausea, and multi-system symptoms that upended her career and finances—while detailing ongoing, multi-specialist care. She describes how careful, low-level activity and a support network enable moments of normalcy, such as buoyancy-assisted diving, underscoring the need for sustained research and accessible treatment for a condition with a broad and evolving impact.

Metformin May Cut Long-COVID Risk When Used During COVID, Review Finds
health2 months ago

Metformin May Cut Long-COVID Risk When Used During COVID, Review Finds

A literature review of randomized trials and health-record analyses suggests that taking metformin during acute COVID-19 can reduce the risk of developing long COVID by roughly 40%–60%, though it is studied for prevention rather than treatment of existing long COVID; findings, including the COVID-OUT trial and EHR-based studies, have replicated this protective effect and point to possible antiviral benefits and compatibility with other antivirals, making metformin a potential low-cost outpatient preventive option.

Zombie COVID Fragments Attack Immune Cells, Fuel Long COVID
science2 months ago

Zombie COVID Fragments Attack Immune Cells, Fuel Long COVID

New research shows leftover fragments from SARS-CoV-2 form protein pieces that bind to curved membranes on immune cells, suppressing dendritic cells and T cells and potentially driving long-COVID; Omicron fragments appear less damaging to these cells, highlighting variant differences while underscoring ongoing COVID risks and the value of vaccination.