"2023 Notre Dame vs. USC: Game Predictions, Odds, and Defense Showdown"

TL;DR Summary
The No. 10 USC Trojans, led by reigning Heisman Trophy winner Caleb Williams, will face off against the No. 21 Notre Dame Fighting Irish in a highly anticipated college football matchup. Williams leads the country in passing efficiency and touchdowns, while Notre Dame boasts a strong defense. USC has the best offense in the nation, but Notre Dame's offense has struggled in recent weeks. The Fighting Irish are favored by 3 points, but the game is expected to be high-scoring.
- Notre Dame vs. USC odds, spread, line: 2023 college football picks, Week 7 predictions from computer model CBS Sports
- Sources - USC star freshman Zachariah Branch game-time decision - ESPN ESPN
- College football this weekend: Can USC’s defense slow down Notre Dame? The Washington Post
- Notre Dame vs USC Game Predictions Sports Illustrated
- USC vs. Notre Dame Prediction, Pick Against the Spread, and Latest Odds OddsChecker
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