49ers' McCaffrey Out with Knee Injury Against Bills

TL;DR Summary
49ers running back Christian McCaffrey has been ruled out of Sunday's game against the Bills due to a knee injury sustained in the first half. McCaffrey, who previously missed eight games this season with bilateral Achilles tendinitis, had rushed for 53 yards and caught two passes before exiting. Jordan Mason has taken over as the leading rusher for San Francisco in McCaffrey's absence. Additionally, the 49ers' defensive tackle Kevin Givens has also been ruled out.
- Christian McCaffrey downgraded to out with knee injury NBC Sports
- 49ers RB McCaffrey (knee) ruled out in Buffalo ESPN
- Niners RB Christian McCaffrey exits Sunday night game vs. Bills with knee injury NFL.com
- 49ers star Christian McCaffrey ruled out after leaving game vs. Bills early with awkward non-contact knee injury Yahoo Sports
- Christian McCaffrey injury update and status vs. the Bills in Week 13 | Dec. 1, 2024 Niners Wire
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