genomics5.345 min read
Rewriting a virus genome exposes AI’s blind spots in biology
1 month ago•Source: Nature
Genomics News
The latest genomics stories, each synthesized from multiple sources with added background and context.
Featured Genomics Stories
View original source
11.2 min•4 months ago
Parental Genes Leave a Lasting Imprint Beyond Inherited DNA
A large international study analyzing over 30,000 families shows that a child’s traits—height, BMI, and school test scores—are shaped not only by their own DNA but also by the environment created by parents’ genes and by parent-of-origin effects. Researchers developed a method to separate direct genetic effects from indirect (genetic nurture) and parent-of-origin effects, finding that parental influences are substantial and that the same genetic regions can influence traits through both inheritance and environment. The findings have broad implications for interpreting genetic studies and shaping policy, suggesting that family environment plays a powerful role and that only direct genetic effects may be ideal drug targets.
More Top Stories
2
Biobank DNA leftovers unlock secrets of Epstein–Barr virus
Nature•8 months ago
3
"NICER: Revolutionizing Gene Editing with Enhanced Safety"
News-Medical.Net•3 years ago
More Genomics Stories
New Human Pangenome Reference Enhances Chromosome Biology Understanding.
Researchers from the University of Tennessee Health Science Center have made a foundational discovery about chromosome biology through their work on the first-ever human pangenome reference. The draft pangenome uses complete genome assemblies to provide a diverse look at the genetic makeup of humans. The pangenome project aims to map the entirety of human genetic variation to create a comprehensive reference for geneticists to use to compare DNA sequences, which can aid in the study of connections between genes and diseases. The UTHSC researchers discovered different acrocentric chromosomes can recombine with each other to exchange DNA through their shorter arms, which was key to solving the most common type of chromosomal abnormality in humans.