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The Impact of Genome Doubling on Cancer Development and Chromatin Segregation.

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Source: Nature.com
The Impact of Genome Doubling on Cancer Development and Chromatin Segregation.
Photo: Nature.com
TL;DR

Cells with doubled genomes experience a shortage of proteins that regulate DNA packing, leading to poor segregation of DNA structures and contributing to cancer development. The cells do not upscale protein synthesis to cope with the increase in DNA, according to a study published in Nature.

Topics:sciencehealth#cancer-development#chromatin-segregation#dna-packing#genome-doubling#health#protein-synthesis
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  1. Genome doubling perturbs DNA packing and promotes cancer development  Nature.com
  2. Single-cell sequencing solution seeks to unleash disruptive science, with a vortexer  Phys.org
  3. Whole-genome doubling drives oncogenic loss of chromatin segregation  Nature.com

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