Younger Generations Biologically Older, Linked to Early-Onset Cancer Risk
New cross-cohort study finds younger birth cohorts are biologically older than earlier generations at the same age, based on PhenoAge from blood biomarkers, and that higher age-gap scores are tied to greater risk of early-onset cancers (lung, digestive system, uterus) even after accounting for smoking, obesity, telomere length, and genetics, suggesting environmental influences on aging and potential for targeted prevention.