Sulfa Labels Hamper Cyclospora Treatment in Outbreak
During a large Cyclospora outbreak, trimethoprim-sulfamethoxazole is the preferred treatment, but a sulfa allergy label pushes clinicians to use less effective and more costly alternatives like nitazoxanide or ciprofloxacin. The article emphasizes careful allergy evaluation and delabeling—often possible—since many sulfa labels are inaccurate, enabling the use of first-line therapy when appropriate.