
Teen’s Cannabis Scromiting Linked to Acute Thiamine-Deficiency Brain Disorder
A 15-year-old with cannabinoid hyperemesis syndrome (CHS) suffered from severe vomiting that led to dangerous vitamin B1 (thiamine) deficiency and signs of Wernicke encephalopathy, a brain disorder usually associated with alcohol misuse. After rapid thiamine treatment, his neurological symptoms improved and he recovered enough to be discharged; he later stopped using cannabis. The case, one of the earliest pediatric CHS-linked instances of this brain condition, underscores the risk of nutritional deficits in CHS and suggests clinicians consider empiric thiamine supplementation in teens with prolonged CHS and new neurologic findings, even if MRI is inconclusive.











