Most Sleep Aids Safe for Obstructive Sleep Apnea, Temazepam Notable Risk
A Japanese-led network meta-analysis of 32 randomized trials across 12 hypnotics in adults with COMISA found that most sleep medications do not significantly worsen respiratory outcomes or oxygen levels compared with placebo; temazepam stood out as potentially lowering nocturnal oxygen saturation. The study supports symptom-driven drug choices and notes CPAP remains the gold standard, with meds offering a viable plan B for those who struggle with CPAP tolerance.