Gabapentin’s mood shifts and a plant-based plan for kidney health
A Dr. Roach column notes gabapentin is FDA-approved for seizures and postherpetic neuralgia but is widely used off-label, with moderate effectiveness for neuropathic pain and notable neurological/psychiatric side effects (emotional lability, aggression, concentration problems, memory issues, and even dementia risk with long-term use), so benefits must be weighed against risks and patients should be closely monitored. The piece also cites evidence favoring plant-based diets for chronic kidney disease, arguing potassium concerns are often overstated due to lower potassium absorption, and endorsing a shift toward more plant-based protein for better outcomes.