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Postexposure Prophylaxis

All articles tagged with #postexposure prophylaxis

Ensitrelvir Emerges as a Key COVID Postexposure Prophylaxis Choice
health29 days ago

Ensitrelvir Emerges as a Key COVID Postexposure Prophylaxis Choice

A Medscape Family Medicine commentary reviews COVID prophylaxis options for high‑risk patients, highlighting ensitrelvir as a postexposure prophylaxis with strong efficacy (RR 0.33) and acceptable safety in a large household-exposure trial, while noting mixed results for nirmatrelvir‑ritonavir and pemivibart (approved as PrEP, with infusion risks). The piece emphasizes educating patients and protecting vulnerable individuals as COVID-19 remains a threat.

Antiviral pill cuts COVID risk after exposure, NEJM trial finds
health4 months ago

Antiviral pill cuts COVID risk after exposure, NEJM trial finds

A five‑day course of ensitrelvir (Xocova) significantly reduced the risk of developing COVID-19 after household exposure in a double‑blind NEJM phase 3 trial of about 2,000 participants: 9% in the placebo group developed symptoms within 72 hours versus 2.9% in the drug group; by day 10, 14% vs 21.5% tested positive. Side effects were similar between groups. The drug is already approved in Japan for treatment and is being considered for post‑exposure prevention by US/EU regulators; pregnancy safety was not studied.

Rabid skunk attack reported near US 64 in Lexington
health2 years ago

Rabid skunk attack reported near US 64 in Lexington

A person was bitten by a rabid skunk near US 64 in Lexington, North Carolina. Animal Control safely removed the skunk and confirmed it had rabies. This is the eighth confirmed case of rabies in Davidson County this year. The person who was bitten sought immediate postexposure prophylaxis treatment. The health department advises against engaging with wild animals, as they are more likely to transmit the potentially deadly virus. Rabies is 99.9% fatal in humans without immediate treatment. State law requires reporting all animal bites to the local health department and vaccinating domestic animals against rabies.

Rabid bat discovered in Woodstock home, family exposed.
health3 years ago

Rabid bat discovered in Woodstock home, family exposed.

A family in Woodstock was recommended to undergo postexposure prophylaxis (PEP) treatment after being possibly exposed to a rabid bat found in their home. The McHenry County Department of Health (MCDH) said that rabies in Illinois is primarily contracted from bats. The MCDH recommends that residents who find a bat in their home contain it in a room by closing the door or placing a blanket on it and notify the MCDH Animal Control. Residents should not touch, feed or unintentionally attract wild animals with open garbage cans or litter.