Teen Cannabis Use Linked to Disrupted Brain Reward Development
A Brown University-led study with 81 adolescents (14–17) found that repeated cannabis use, especially high-potency products, correlates with lower brain tissue iron in dopamine-rich regions, signaling disrupted maturation of the dopamine system and reward processing. This first-of-its-kind MRI work suggests reduced dopamine-related neurophysiology in teens who use cannabis and highlights potential increased addiction vulnerability, warranting longitudinal follow-up to assess long-term outcomes.