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PTGES3 Identified as Key Regulator of Androgen Receptor in Prostate Cancer

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Source: Nature
PTGES3 Identified as Key Regulator of Androgen Receptor in Prostate Cancer
Photo: Nature
TL;DR

Genome-scale CRISPR screens identified PTGES3 as a key regulator of androgen receptor (AR) stability and activity in advanced prostate cancer, revealing its potential as a therapeutic target to overcome resistance to AR-targeted therapies in castration-resistant prostate cancer (CRPC).

Topics:healthcancer-research#androgen-receptor#cancer-research#crispr-screens#prostate-cancer#ptges3#therapy-resistance
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Genome-scale CRISPR screens identify PTGES3 as a direct modulator of androgen receptor function in advanced prostate cancer  Nature

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