Shingrix could cut heart attack and stroke risk, big US study suggests

A US study of about 70,000 adults aged 60+ found Shingrix vaccination was linked to a 12% reduction in cardiovascular events (heart attack, stroke, heart failure) over 3.5 years, with a 4% reduction by the end of follow-up. While the absolute risk change is small, the potential population impact could be large; if confirmed in randomized trials, the effect would be comparable to taking antihypertensive meds. Researchers are exploring mechanisms (reduced shingles risk or broader immune effects) and more trials are underway.