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Shingrix

All articles tagged with #shingrix

health6 days ago•7 min saved

Shingrix May Help Heart Health, Study Suggests

An observational study of more than 70,000 adults 60+ found that those who received the Shingrix shingles vaccine had a lower risk of cardiovascular disease, heart failure, and stroke compared with those who got the older Zostavax vaccine, including about 9% longer cardiovascular disease-free time and 12% lower heart disease risk (and a 12% lower stroke risk in men). The study shows association, not causation, but researchers say preventing shingles may reduce vascular inflammation and immune activation; the vaccine’s AS01 adjuvant could play a role. Experts stress continuing established heart-healthy practices and note only about 42% of eligible adults are vaccinated, with access and cost issues influencing uptake.

via Prevention|

#cardiovascular-disease #health #inflammation

health8 days ago•6 min saved

Shingrix linked to lower dementia risk in older adults, study suggests

A Brown University study of more than 509,000 adults aged 66+ found that those who had at least one Shingrix dose showed a 24% relative reduction in dementia diagnoses over four years versus unvaccinated peers, based on electronic health records and Medicare data; researchers stress this is an association, not proof of causation, and the vaccine’s primary purpose is shingles prevention, though explanations include fewer shingles-related complications and potential vascular benefits. The study was funded by GSK.

via Fox News|

#dementia-risk #health #observational-study

health8 days ago•46 min saved

Shingles vaccine may be linked to reduced dementia risk, neurologist says

Neurologist Dr. Ajeet Sodhi explains that while some research links the shingles vaccine to a lower dementia risk, the findings show an association rather than proof of causation, and more studies are needed to establish any definitive protective effect.

via Yahoo|

#ajeet-sodhi #dementia-risk #health

science8 days ago•22 min saved

Shingrix Could Protect the Heart for Years, Study Suggests

A US study of about 70,000 adults aged 60+ found that the recombinant shingles vaccine Shingrix is associated with a lower risk of cardiovascular disease years after vaccination compared with the older live vaccine, with the strongest effect on ischemic heart disease and heart failure; the finding hints at immune-system changes beyond shingles, though the observational design aims to reduce bias by comparing groups who chose vaccination rather than vaccinated versus unvaccinated.

via ZME Science|

#cardiovascular-disease #immune-system #observational-study

health9 days ago•3 min saved

Shingrix could cut heart attack and stroke risk, big US study suggests

A US study of about 70,000 adults aged 60+ found Shingrix vaccination was linked to a 12% reduction in cardiovascular events (heart attack, stroke, heart failure) over 3.5 years, with a 4% reduction by the end of follow-up. While the absolute risk change is small, the potential population impact could be large; if confirmed in randomized trials, the effect would be comparable to taking antihypertensive meds. Researchers are exploring mechanisms (reduced shingles risk or broader immune effects) and more trials are underway.

via The Guardian|

#cardiovascular #health #shingles

pharma1 month ago•3 min saved

GSK kicks off large trial to test shingles vaccine for dementia prevention

GSK is launching a large study to determine whether the shingles vaccine Shingrix can lower dementia risk, prompted by observational data suggesting vaccinated individuals may have fewer dementia cases; the trial aims to establish causality and could influence dementia prevention strategies if results are favorable.

via Endpoints News|

#alzheimers-disease #dementia-prevention #gsk

health2 months ago•7 min saved

Shingles Shots May Shield Older Brains From Dementia

New research across the U.S. and other countries finds that receiving the shingles vaccine—especially Shingrix—might lower dementia risk in older adults by reducing brain inflammation, though most studies are observational and benefits vary by sex and prior vaccination; vaccination rates are still low despite potential protection.

via NBC News|

#brain-inflammation #dementia #health

health2 months ago•7 min saved

Shingrix Vaccine Linked to Lower Dementia Risk in Nursing Home Residents

A Brown University-led analysis of more than 500,000 Medicare beneficiaries found that older adults who received the Shingrix shingles vaccine after entering skilled nursing facilities had about 24% fewer dementia diagnoses over four years compared with those unvaccinated, though the study cannot prove causation and residual differences between groups may influence results.

via SciTechDaily|

#dementia #elderly #gerontology

health2 months ago•5 min saved

Shingrix May Cut Dementia Risk by 24% in Seniors, Study Finds

A real-world study of 509,926 nursing‑facility residents found that those who received the Shingrix shingles vaccine within 12 months of admission had a 24% lower risk of developing dementia over four years than unvaccinated peers, though the observational design cannot establish causation. Uptake was low (8,843 vaccinated), and researchers note potential neuroinflammatory mechanisms and confounders; the study was funded by GlaxoSmithKline, and Shingrix’s real‑world cognitive benefits add to questions about why vaccines might protect brain health.

via ScienceAlert|

#dementia #elderly #health

health4 months ago•4 min saved

Shingrix May Cut Dementia Risk in Older Americans, Large Study Finds

A large U.S. Medicare study (1.5 million beneficiaries) found that older adults who received the two-dose recombinant zoster vaccine (Shingrix) had a lower incidence of dementia than unvaccinated peers, with about a 28–33% reduced risk for any dementia, Alzheimer's disease, and vascular dementia over up to three years and continued protection beyond three years; results are observational and can’t prove causality, but align with other real-world evidence and call for trials to confirm.

via MedPage Today|

#alzheimers-disease #dementia #health

health4 months ago•10 min saved

FDA Suppressed Vaccine-Benefit Studies, New Reports Say

Ars Technica, citing The New York Times, reports that the FDA blocked publication of studies on COVID-19 and Shingrix vaccines showing benefits; the CDC reportedly scrapped a separate vaccine study. HHS says withdrawals protected scientific integrity, but critics frame the moves as censorship connected to RFK Jr.’s anti-vaccine agenda under his health department.

via Ars Technica|

#censorship #covid-19 #fda

health4 months ago•1 min saved

FDA pulls back vaccine-safety studies amid political pressure controversy

The FDA reportedly withdrew several studies supporting the safety of COVID-19 and Shingrix vaccines after officials said the authors drew broad conclusions not supported by the data, a move CNBC linked to ongoing Trump-era efforts to scrutinize vaccines; agency scientists analyzed large datasets to assess side effects and said the withdrawal was to protect scientific integrity.

via CNBC|

#covid-19 #fda #health

health5 months ago•7 min saved

Shingles Vaccine Linked to Lower Dementia Risk, Early Studies Hint

New studies suggest the Shingrix shingles vaccine may be associated with a lower risk of dementia in older adults, with some research indicating about a 50% reduction in risk among vaccinated individuals. In addition to preventing shingles and its serious complications like postherpetic neuralgia, the vaccine may also modestly lower risks of heart attack and stroke. The CDC recommends two doses for adults 50+, with dosing intervals of two to six months, and stronger immune responses are reported in older adults. Side effects are usually mild, and vaccination rates for adults over 60 remain around 35%; more research is needed to establish causality between vaccination and dementia protection.

via The Guardian|

#dementia #health #prevention

health6 months ago•8 min saved

Shingles vaccine tied to lower dementia risk, with newer shots showing stronger signals

Natural-experiment studies across Wales, Australia, Canada, and the US consistently link shingles vaccination with reduced dementia risk, and newer data suggest that Shingrix may offer larger protective benefits than the older Zostavax—potentially by lowering brain inflammation from varicella-zoster reactivation—though causality and gender differences require further study.

via Ars Technica|

#aging #dementia #health

health10 months ago•4 min saved

Shingles Vaccine and Its Potential Role in Reducing Dementia Risk

A large study suggests that receiving the shingles vaccine, particularly the newer Shingrix, may be associated with a reduced risk of developing dementia in older adults, possibly due to decreased viral reactivation or immune system effects, though further research is needed to confirm causality.

via Earth.com|

#brain-health #dementia #health