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Shingrix

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Shingrix May Cut Dementia Risk in Older Americans, Large Study Finds
health18 days ago

Shingrix May Cut Dementia Risk in Older Americans, Large Study Finds

A large U.S. Medicare study (1.5 million beneficiaries) found that older adults who received the two-dose recombinant zoster vaccine (Shingrix) had a lower incidence of dementia than unvaccinated peers, with about a 28–33% reduced risk for any dementia, Alzheimer's disease, and vascular dementia over up to three years and continued protection beyond three years; results are observational and can’t prove causality, but align with other real-world evidence and call for trials to confirm.

FDA pulls back vaccine-safety studies amid political pressure controversy
health20 days ago

FDA pulls back vaccine-safety studies amid political pressure controversy

The FDA reportedly withdrew several studies supporting the safety of COVID-19 and Shingrix vaccines after officials said the authors drew broad conclusions not supported by the data, a move CNBC linked to ongoing Trump-era efforts to scrutinize vaccines; agency scientists analyzed large datasets to assess side effects and said the withdrawal was to protect scientific integrity.

Shingles Vaccine Linked to Lower Dementia Risk, Early Studies Hint
health2 months ago

Shingles Vaccine Linked to Lower Dementia Risk, Early Studies Hint

New studies suggest the Shingrix shingles vaccine may be associated with a lower risk of dementia in older adults, with some research indicating about a 50% reduction in risk among vaccinated individuals. In addition to preventing shingles and its serious complications like postherpetic neuralgia, the vaccine may also modestly lower risks of heart attack and stroke. The CDC recommends two doses for adults 50+, with dosing intervals of two to six months, and stronger immune responses are reported in older adults. Side effects are usually mild, and vaccination rates for adults over 60 remain around 35%; more research is needed to establish causality between vaccination and dementia protection.

Shingles vaccine tied to lower dementia risk, with newer shots showing stronger signals
health2 months ago

Shingles vaccine tied to lower dementia risk, with newer shots showing stronger signals

Natural-experiment studies across Wales, Australia, Canada, and the US consistently link shingles vaccination with reduced dementia risk, and newer data suggest that Shingrix may offer larger protective benefits than the older Zostavax—potentially by lowering brain inflammation from varicella-zoster reactivation—though causality and gender differences require further study.