Ketamine Sparks Female-Specific Brain Plasticity via Microglia
TL;DR Summary
A study finds that after ketamine anesthesia, female mice exhibit heightened brain activity and microglial remodeling that increases neuroplasticity via corticosterone triggering the FKBP51 protein; this effect is not observed in male mice, suggesting sex-specific drug responses with implications for depression treatment research.
- Ketamine boosts neuroplasticity through microglia in female brains News-Medical
- Microglia reveal sex-specific brain recovery mechanism after ketamine anesthesia Medical Xpress
- The Female Brain Wakes Up Differently After Ketamine Anesthesia Technology Networks
- Ketamine Reshapes Neural Networks and Neuroplasticity Neuroscience News
- Ketamine Can Be a Go-To Anesthetic in Emergencies, but It May Affect Male and Female Brains Differently Discover Magazine
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