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Lung-resident immune cells link genetics to autoimmune risk

1 min read
Source: News-Medical
Lung-resident immune cells link genetics to autoimmune risk
Photo: News-Medical
TL;DR

Researchers analyzed over 1.1 million tissue-resident lung immune cells from 128 donors using single-cell RNA-seq, revealing that genetic risk factors shape lung immune cell function and can drive autoimmune and inflammatory disease; thousands of risk-associated genes are active in tissue cells but not in blood, and about 1,700 genes show sex-specific expression, suggesting sex-based factors in disease susceptibility.

Topics:healthlife-sciences#autoimmune-disease#genetic-risk-factors#life-sciences#lung-immunology#single-cell-rna-seq#tissue-resident-immune-cells
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  1. Study of lung immune cells uncovers roots of autoimmune disease  News-Medical
  2. Immune cells in human lung tissue may drive the development of autoimmune disease  Medical Xpress
  3. Tissue-resident immune cells drive genetic risk in autoimmune and lung diseases  Nature
  4. Lung Immune Cells Protect Against Respiratory Infections  respiratory-therapy.com
  5. This Is What Really Happens Inside Your Lungs After Every Illness  MindBodyGreen

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