Brain-Skin Nerve Circuit Ties Stress to Eczema Flares

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Source: ScienceAlert
Brain-Skin Nerve Circuit Ties Stress to Eczema Flares
Photo: ScienceAlert
TL;DR

A Science study shows a brain-to-skin neural circuit where stress activates sympathetic nerves that drive eosinophils, worsening eczema. In mice, reducing eosinophils diminished the stress-related flare, while in humans higher stress correlated with more inflammation and eosinophils, suggesting potential therapies that target this neuroimmune pathway to alleviate eczema symptoms.

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