Cannabis Use Linked to Higher Testosterone and Hormonal Shifts in Young Men

A Swiss study of 94 young men found cannabis users had about 23% higher testosterone than non-users, plus raised levels of androstenedione and DHT, while adrenal androgens were unchanged. The effects appear localized to the testes, with two progesterone‑related metabolites also elevated, suggesting cannabis alters a broader hormonal network rather than simply lowering testosterone. The brain’s role remains uncertain, and implications for fertility are not yet clear.