EPA in Fish Oil Linked to Slower Brain Repair After Repeated Head Injuries

A MUSC study published in Cell Reports shows that EPA, an omega-3 fatty acid in fish oil, can hinder brain repair after repetitive mild traumatic brain injuries, while DHA remains generally beneficial; in mice and human endothelial cells EPA reduced repair and angiogenesis, with postmortem CTE tissue showing related lipid and vascular changes. The authors caution that omega-3 effects are context-dependent and not universally protective, urging more research into precision nutrition and EPA handling in the brain.