Global AMR wave: common infections resisting antibiotics worldwide

A global review led by Jilin University and Peking Union Medical College Hospital finds antimicrobial resistance (AMR) is not a distant threat but a present crisis: common infections are increasingly no longer treatable with standard antibiotics, with regional patterns influenced by policy, practice, and environmental use; bacteria such as E. coli and Klebsiella show β-lactamase activity in parts of Asia while carbapenem resistance climbs in Europe and the Americas, and fungi like Candida auris also resist multiple drugs. Reversing the trend requires rapid diagnostics, precision dosing, smarter drug combinations, and robust national surveillance and stewardship, plus cutting agricultural antibiotic use and pursuing new antibiotics and antifungals within a One Health framework. The study appears in the Medical Journal of Peking Union Medical College Hospital.