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Antimicrobial Resistance

All articles tagged with #antimicrobial resistance

Wild tormentil uncovers plant compounds that fend off superbugs and boost antibiotics
health2 days ago

Wild tormentil uncovers plant compounds that fend off superbugs and boost antibiotics

A study screening bogland plants found tormentil (Potentilla erecta) extracts to be antimicrobial, to limit biofilm formation, and to enhance the effectiveness of the last-resort antibiotic colistin when used together, via compounds like ellagic acid and agrimoniin that appear to work by iron chelation; this highlights plant compounds as sources of new antimicrobials and antibiotic adjuvants amid rising antimicrobial resistance.

via The Conversation|
#antimicrobial-resistance#biofilms#combination-therapy
Microplastics fuel global spread of antibiotic‑resistant bacteria via biofilms
environment23 days ago

Microplastics fuel global spread of antibiotic‑resistant bacteria via biofilms

A Plymouth Marine Laboratory–Exeter study shows microplastics act as mobile surfaces for microbial communities, forming dense biofilms (the Plastisphere) that carry antibiotic‑resistance genes and potentially resistant pathogens. These plastics can transport microbes from hospital wastewater to rivers and oceans, with downstream and marine environments showing higher resistance gene levels, especially on polystyrene and nurdles. The findings highlight the need for closer monitoring of microplastics, reducing plastic pollution, and careful handling during beach cleanups to protect ecosystems and human health.

via Earth.com|
#antimicrobial-resistance#biofilms#environment
Dentists still prescribe millions of clindamycin despite life-threatening C. difficile risk
health1 month ago

Dentists still prescribe millions of clindamycin despite life-threatening C. difficile risk

Dentists prescribed over 2.3 million clindamycin prescriptions last year despite a decades‑old black‑box warning for serious C. difficile infections, even as overall dental antibiotic use rose about 6% from 2020 to 2025. The investigation ties unnecessary dental antibiotic prescribing to higher C. difficile risk and antimicrobial resistance, highlighting how private dental practice has lagged in antibiotic stewardship and guideline updates, with the story of Dolores Owens illustrating the potential harms of such prescribing.

via CIDRAP|
#antibiotic-stewardship#antimicrobial-resistance#c-difficile
Space Mutations Boost Phages in the Battle Against Superbugs
science2 months ago

Space Mutations Boost Phages in the Battle Against Superbugs

A UW–Madison-led study compared a E. coli–T7 phage clash on Earth and in microgravity aboard the ISS. In space, phages infect more slowly but still acquire mutations that improve their ability to bind bacterial receptors, while the bacteria develop space-specific defenses—demonstrating space-driven evolutionary paths that could inform phage-based strategies against drug‑resistant pathogens on Earth.

via Yahoo|
#antimicrobial-resistance#bacteriophage#evolution
health-and-science6 months ago

AI-Driven Discoveries in the Fight Against Superbugs

Dr. Fred Mutisya, a Kenyan medical doctor and AI innovator, developed antimicro.ai, an open-source AI tool to analyze data on antimicrobial resistance (AMR). His work aims to improve antibiotic use and combat AMR, which poses a significant global health threat. While successful in Europe, the tool has yet to be adopted widely in Kenya, highlighting challenges in local healthcare innovation adoption.

via Daily Nation|
#ai-innovation#antimicrobial-resistance#health-and-science
Ancient Bacteriophages Offer New Hope Against Superbugs
science7 months ago

Ancient Bacteriophages Offer New Hope Against Superbugs

Imperial College London researchers discovered how 'pirate phages' hijack other viruses to transfer genetic material between bacteria, potentially advancing new treatments for drug-resistant infections and enhancing rapid diagnostics. They found that cf-PICIs hijack tails from unrelated phages to broaden their host range, facilitating the spread of resistance traits. This understanding could lead to innovative therapies and diagnostic tools, with ongoing efforts to develop applications and validate AI-driven research acceleration.,

via Imperial College London|
#antimicrobial-resistance#bacteriophages#biomedical-research