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KAIST Develops CRISPR-Based System for Precise RNA Modification in Living Cells

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Source: Phys.org
KAIST Develops CRISPR-Based System for Precise RNA Modification in Living Cells
Photo: Phys.org
TL;DR

KAIST researchers developed a precise RNA modification technology using CRISPR-Cas13 and a hyperactive NAT10 variant, enabling targeted acetylation of specific RNAs in living cells and animals, which could advance RNA-based therapies and gene regulation research.

Topics:healthscience#crispr-cas13#gene-therapy#in-vivo#rna-acetylation#rna-modification#science
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  1. CRISPR-Cas13 allows selective modification of desired RNA in living cells  Phys.org
  2. Targeted RNA acetylation via a dCas13-guided engineered acetyl-transferase  Nature
  3. KAIST pioneers targeted RNA acetylation system for gene therapy advancements  Chosun Biz
  4. New CRISPR tool enables precise chemical modification of RNA in living cells  News-Medical

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