Meiosis-Targeted Breakthrough Moves Toward Reversible Nonhormonal Male Contraception
TL;DR
Cornell researchers in mice used the small molecule JQ1 to block meiosis at prophase 1, halting sperm production for three weeks with fertility and normal offspring restored within six weeks after stopping treatment, providing a proof of principle for a safe, reversible, nonhormonal male contraceptive; the team plans to pursue additional meiosis targets and aim to develop a long-acting delivery method (injection or patch) and even launch a company to advance these candidates.
- Breakthrough takes big step toward safe, reversible male contraception Cornell Chronicle
- Scientists Find Reversible Male Birth Control That Stops Sperm Production NDTV
- Scientists Achieve Major Breakthrough in Safe, Reversible Male Contraception Bioengineer.org
- New Step Towards Male Contraception As Sperm Production Blocked Safely And Reversibly Without Hormones IFLScience
- Male birth control that STOPS sperm production is '100% effective' & reversible The Sun
Want the full story? Read the original reporting
Read on Cornell Chronicle