FDA warns against using amniotic fluid as eye drops.

The FDA has issued a public safety notification warning people not to use eye drops containing amniotic fluid, which is largely fetal urine, to treat eye conditions such as dry eyes and inflammation. The drops are unapproved and require an investigational new drug application and full FDA approval before hitting the market. The agency has found unapproved products on the market, raising potential significant safety concerns, and there is only one published clinical trial of amniotic fluid eye drops, which found them to be ineffective.