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Key Genetic and Developmental Changes Behind Human Bipedalism

1 min read
Source: Nature
Key Genetic and Developmental Changes Behind Human Bipedalism
Photo: Nature
TL;DR

The article explores the developmental genetic changes that led to the evolution of hominin bipedalism, focusing on two key innovations: a shift in iliac cartilage growth plate orientation and a delayed, altered pattern of iliac ossification. These changes facilitated the unique shape and function of the human pelvis, supporting upright walking, and are driven by polygenic regulatory modifications involving genes like SOX9, PTH1R, and RUNX2, with evidence of human-specific evolutionary signals in these regions.

Topics:top-newsscience#bipedalism#genetic-innovations#hominin-evolution#human-evolution#pelvic-development#science
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  1. The evolution of hominin bipedalism in two steps  Nature
  2. Uncovering the Genes That Let Our Ancestors Walk Upright  The New York Times
  3. Two evolutionary changes underpinning human bipedalism are discovered  Reuters
  4. Irish scientist helps crack mystery of how humans came to stand on two legs  The Irish Independent
  5. Two Changes in Bone Development Allowed Humans to Stand on Two Legs  the-scientist.com

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