Week 2 NFL Predictions: Experts Forecast Every Week 2 Game

TL;DR
This article compiles expert predictions and betting odds for every Week 2 NFL game, headlined by the Bills–Lions Thursday night matchup. It lists each game with date, location, spread, and selected takes from outlets like CBS Sports, Sporting News, and more, with BetMGM odds cited as of Sept. 15, 2026.
- NFL Week 2 game picks: Odds and expert predictions for every matchup USA Today
- Seven things Solak thinks entering NFL Week 2 espn.com
- 2026 NFL Week 2 odds, score predictions: SportsLine AI reveals picks for every game SportsLine
- NFL best bets Week 2: Leaning into unders, including Colts-Chiefs The New York Times
- Week 2 NFL odds, picks, predictions: Computer model backs Seahawks and Buccaneers CBS Sports
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