
SportsLine Model Favors Lions and 49ers in NFL Week 3
SportsLine’s computer model, which simulates every game 10,000 times, identifies the Detroit Lions and San Francisco 49ers as top betting picks for NFL Week 3. The model projects Detroit to cover a 6.5-point spread against the Jets and San Francisco to cover 8.5 points against the Cardinals. Key factors include Detroit’s strong record after losses and San Francisco’s top-five rankings in both offense and defense. The model has a 53-41 record on top-rated picks since 2024.













