
Low-dose quetiapine may worsen next-day alertness in sleep apnea patients
A small trial (15 participants) in obstructive sleep apnea found that low-dose quetiapine can extend sleep but impairs next-day cognitive function and driving performance, with slower reaction times and more attention lapses; some did not feel sleepy despite worse performance. The study cautions against using quetiapine as routine sleep medication for sleep apnea and calls for larger, longer studies and more personalized treatment approaches.
