Tag

Alertness

All articles tagged with #alertness

Low-dose quetiapine may worsen next-day alertness in sleep apnea patients
health2 months ago

Low-dose quetiapine may worsen next-day alertness in sleep apnea patients

A small trial (15 participants) in obstructive sleep apnea found that low-dose quetiapine can extend sleep but impairs next-day cognitive function and driving performance, with slower reaction times and more attention lapses; some did not feel sleepy despite worse performance. The study cautions against using quetiapine as routine sleep medication for sleep apnea and calls for larger, longer studies and more personalized treatment approaches.

New Drug Outperforms Caffeine in Fighting Daytime Sleepiness.
health3 years ago

New Drug Outperforms Caffeine in Fighting Daytime Sleepiness.

Solriamfetol, a prescription drug, has emerged as a promising alternative to caffeine for promoting alertness, particularly in patients with Obstructive Sleep Apnea (OSA) and Excessive Daytime Sleepiness (EDS). Unlike caffeine, which inhibits adenosine receptors, solriamfetol increases the levels of dopamine and norepinephrine – neurotransmitters linked to wakefulness. Solriamfetol maintains wakefulness for as long as nine hours, requiring less frequent dosing and minimizing sleep disruption risk. However, it can cause side effects such as headache, nausea, and decreased appetite, and carries a risk of abuse and dependency.