Tag

Fsgs

All articles tagged with #fsgs

biotechnologyhealth1 month ago•18 min saved

First FDA-approved therapy for FSGS: FILSPARI wins full approval

The FDA granted full approval for FILSPARI (sparsentan) to reduce proteinuria in adults and children 8+ with focal segmental glomerulosclerosis (FSGS) without nephrotic syndrome, making it the first FDA-approved treatment for this rare kidney disease and expanding the U.S. addressable population to over 100,000 patients with FSGS and IgAN. In the Phase 3 DUPLEX trial, FILSPARI achieved a 46% reduction in proteinuria overall (48% in non-nephrotic patients) versus irbesartan, with a safety profile similar to irbesartan; however, hepatotoxicity risk requires REMS and there are important pregnancy contraindications and drug interactions, including avoidance with ARBs/ERAs and certain CYP3A modulators. Travere will host a conference call to discuss the approval.

via Business Wire|

#biotechnologyhealth #fdaapproval #filspari

health2 years ago•1 min saved

"Brave Gwinnett Woman Succumbs to Long Battle with Kidney Disease"

Ramonie Smith, a young woman from Gwinnett County, Georgia, has passed away after a long battle with kidney disease and heart disease, including a stroke. Smith, who lived with a rare kidney disease called FSGS, had received a kidney transplant at the age of 5 but needed another transplant as the illness returned. Despite efforts to find a match through billboards and a GoFundMe campaign, only one percent of the population would have been a suitable donor. Smith's family has set up a GoFundMe campaign to help with funeral expenses.

via WSB Atlanta|

#fsgs #gwinnett-county #health