All articles tagged with #lacunar stroke
New research links lacunar (small vessel) stroke to enlargement and damage of the brain’s tiny vessels rather than fatty plaque in large arteries, explaining why aspirin often fails and guiding new therapies targeting the brain’s microvasculature, such as those tested in the LACI-3 trial.
A 229-person study links lacunar stroke to widening of brain arteries and microvascular disease, not fatty blockages in large vessels, explaining why antiplatelet drugs often underperform and steering research toward microvascular–targeted therapies like those in the LACI-3 trial.
A new study finds lacunar strokes are more strongly linked to widening and elongation of small brain arteries and microvascular damage (cerebral small vessel disease) than to narrowing of large arteries. This challenges the standard focus on preventing artery blockages and suggests current antiplatelet/statin therapies may be less effective for this stroke type. The findings also highlight a need for treatments targeting microvascular health, with the LACI-3 trial testing cilostazol and isosorbide mononitrate to protect small vessels and reduce cognitive decline.