Tag

Minocycline

All articles tagged with #minocycline

health29 days ago•90 min saved

Rosacea antibiotic linked to blue-gray skin patches: a minocycline side effect

A 68-year-old woman developed blue-gray patches on her arms, legs, and tongue within about two weeks of starting the rosacea antibiotic minocycline. Doctors diagnosed type II minocycline-induced hyperpigmentation, a known pigment-related side effect where drug metabolites bind iron and accumulate in macrophages, sometimes lasting after the drug is stopped. She stopped taking the medication and avoided sun exposure, and the patches faded somewhat over six months but persisted in places.

via Live Science|

#adverse-drug-reaction #blue-gray-discoloration #health

health1 month ago•4 min saved

Old Antibiotic, New Panic Aid: Minocycline Shows Promise

A study suggests repurposing minocycline, an existing antibiotic, to treat panic attacks: in both mice and humans exposed to CO2 it reduced panic severity and dampened microglia-driven inflammation, offering a potential faster route to approval and a mechanism distinct from clonazepam, though larger trials and considerations about antibiotic resistance are needed.

via ScienceAlert|

#clonazepam #co2-inhalation #health

health-medical-research2 years ago•2 min saved

"Inflammation-Reducing Drug Ineffective for Dry Age-Related Macular Degeneration, NIH Trial Finds"

A phase II clinical study at the National Eye Institute (NEI) found that the drug minocycline, which reduces inflammation, did not slow vision loss or geographic atrophy expansion in people with dry age-related macular degeneration (AMD). The trial, led by Tiarnan Keenan, M.D., Ph.D., tested whether inhibiting microglia with minocycline might help slow geographic atrophy expansion and its corresponding vision loss, but found no difference in geographic atrophy expansion rate or vision loss with minocycline. The study was funded by the NEI Intramural Program and took place at the NIH Clinical Center.

via National Institutes of Health (NIH) (.gov)|

#amd #clinical-trial #health-medical-research