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New England Journal Of Medicine

All articles tagged with #new england journal of medicine

mRNA flu shot beats standard vaccine in major trial, FDA decision looming
health29 days ago

mRNA flu shot beats standard vaccine in major trial, FDA decision looming

In a Phase 3 trial of more than 40,000 adults aged 50+, Moderna's mRNA influenza vaccine reduced illness to about 2.0% vs 2.8% for standard vaccines (roughly 27% more effective), with similar improvement in adults 65+. Side effects were mild. The FDA decision on licensure is expected by Aug. 5, as Moderna pursues approval; no mRNA flu vaccine is approved anywhere yet.

The Mysterious Decline of a Nonstop Crying Baby
health-pediatrics2 years ago

The Mysterious Decline of a Nonstop Crying Baby

A detailed case report in the New England Journal of Medicine describes the puzzling case of an 8-week-old baby who began crying more and became increasingly irritable before rapidly declining. Despite numerous tests, including blood work, x-rays, and ultrasounds, doctors were unable to determine the cause. The baby eventually showed signs of lethargy, difficulty breathing, and muscle weakness, leading to intubation and mechanical ventilation in the pediatric intensive care unit.