Tag

Obefazimod

All articles tagged with #obefazimod

Abivax shares rise on reassuring safety data for UC drug as NDA looms
business21 days ago

Abivax shares rise on reassuring safety data for UC drug as NDA looms

Abivax’s late‑stage data on obefazimod show malignancies at rates consistent with ulcerative colitis background risk, easing prior cancer concerns and sending the stock up about 34%; the company reiterates plans to file an FDA NDA in Q4 2026, with a Crohn’s trial due mid‑2027 and roughly 37% of initial non‑responders achieving remission after ~10 months on 50 mg. Analysts like Jefferies call the update supportive but warn that generalist investors may still hesitate amid cancer risk, cash needs, and takeover chatter.

Abivax UC drug delivers strong remission in Phase 3, but safety signals spark caution
healthcare1 month ago

Abivax UC drug delivers strong remission in Phase 3, but safety signals spark caution

Abivax’s ulcerative colitis therapy obefazimod showed high remission rates in a 580-patient Phase 3 maintenance trial, with about 51% remission at both 25 mg and 50 mg doses over 44 weeks versus 10.4% with placebo, suggesting strong efficacy. However, the company reported a few cancer cases among treated patients, raising safety concerns and sending shares lower after the results were disclosed.