Antiseizure Drug Shows Promise as a Sleep Apnea Pill
A Phase II trial with 298 adults with untreated moderate-to-severe obstructive sleep apnea found that taking the old anticonvulsant sultiame before bed significantly reduced apnea episodes and improved sleep quality, with the highest dose yielding up to a 47% reduction in events. While promising for those who can’t tolerate CPAP, researchers say longer studies are needed to confirm durability and safety, as part of a broader move toward pill-based apnea treatments that includes other drugs in development like AD109 and tirzepatide.
