Tag

Lancet

All articles tagged with #lancet

health9 days ago•1 min saved

Australian Study Links Persistent BV to Microbiome Failure and Partner Re-infection

Australian researchers identified two distinct pathways for recurrent bacterial vaginosis (BV): failure to clear the infection during treatment and re-infection from partners. Published in The Lancet, the study of 188 couples found that while concurrent partner treatment reduced recurrence by over 60%, approximately one-third of women did not achieve optimal vaginal microbiome recovery after a week of antibiotics, making them nearly three times more likely to relapse within four weeks.

via The Guardian|

#bacterial-vaginosis #health #lancet

health1 month ago•15 min saved

Daily alcohol use linked to higher cancer deaths, new study finds

A Lancet study analyzing three decades of US data shows that alcohol substantially contributes to cancer deaths, with alcohol-related mortality rising about 58% from 1990 to 2023. The risk spans multiple cancers (including breast, liver, colorectal, stomach, pancreatic, and head/neck cancers), and even one standard drink per day can raise cancer risk. While overall cancer deaths have fallen, the share attributable to alcohol has increased, prompting calls to limit consumption; industry groups dispute a blanket “no safe level” claim. The study also notes age- and sex-specific differences, with younger adults and women showing higher relative risk at lower consumption levels. The bottom-line message: reducing alcohol intake to the lowest possible level is best for health.

via KSL News|

#alcohol #cancer #health

health3 months ago•80 min saved

Tiny Brain, Huge Ventricles: A Surprising Case Behind Leg Weakness

A 44-year-old man in France presented with two weeks of left‑leg weakness. Neuroimaging showed an abnormally small brain (about half the average size) with massive fluid buildup and extremely dilated ventricles pushing brain tissue against the skull, a state likely causing his weakness. He had a history of an infancy shunt that was removed at 14. Doctors drained the excess fluid and inserted a new intracranial shunt, with his neurological exams improving over weeks. Neuropsych tests placed his IQ at about 75 and remained unchanged. The Lancet case report uses this vignette to reflect on human brain growth and its drivers, illustrating how a very small brain can be linked to significant clinical changes when ventricles are enlarged.

via Live Science|

#brain #case-report #health

health5 months ago•5 min saved

PCOS Rebrands as PMOS to spotlight endocrine-metabolic ovarian syndrome

Global experts publish in The Lancet a multiyear, multistakeholder process renaming polycystic ovary syndrome (PCOS) to Polyendocrine Metabolic Ovarian Syndrome (PMOS) to avoid the cyst misnomer and better reflect its hormonal and metabolic features, with an eight‑stage plan—from dissemination and resource development to health‑system integration, policy alignment, and international guideline updates—aimed at clearer diagnosis and improved care.

via Contemporary OB/GYN|

#endocrinology #health #health-policy

health6 months ago•9 min saved

Lancet retracts 1977 unsigned talc commentary after uncovering Johnson & Johnson ties

The Lancet has retracted a 1977 unsigned commentary on cosmetic talc after discovering the author was a paid Johnson & Johnson consultant, revealing an undeclared conflict of interest; editors say such unsigned pieces would not be published today, and the decision comes amid decades of talc-related litigation and ongoing debates over asbestos testing in cosmetics, including a FDA rule proposal later withdrawn in 2025.

via Retraction Watch|

#conflicts-of-interest #health #johnson-and-johnson

health6 months ago•2 min saved

New review finds cannabis medicines offer minimal relief for most mental health disorders

A Lancet-published review of 54 randomized trials (1980–2025, 2,477 participants) found cannabis-based medicines provide little to no benefit for most mental health and substance-use disorders such as anxiety, psychotic disorders, PTSD and opioid-use disorder; some limited benefits were seen for cannabis-use disorder withdrawal, Tourette’s tic severity, and certain autistic traits or insomnia, but overall the evidence quality is low and more high-quality trials are needed as medical cannabis use expands.

via Reuters|

#clinical-trials #health #lancet

health7 months ago•16 min saved

Antiseizure Drug Shows Promise as a Sleep Apnea Pill

A Phase II trial with 298 adults with untreated moderate-to-severe obstructive sleep apnea found that taking the old anticonvulsant sultiame before bed significantly reduced apnea episodes and improved sleep quality, with the highest dose yielding up to a 47% reduction in events. While promising for those who can’t tolerate CPAP, researchers say longer studies are needed to confirm durability and safety, as part of a broader move toward pill-based apnea treatments that includes other drugs in development like AD109 and tirzepatide.

via Gizmodo|

#health #lancet #obstructive-sleep-apnea

world7 months ago•4 min saved

Lancet survey puts Gaza war toll far above official counts in first 16 months

A Lancet Global Health study based on a representative survey of 2,000 Gaza families estimates more than 75,000 people were killed in the first 16 months of the Gaza war—about 25,000 more than Gaza’s health ministry reported at the time—with 42,200 of those deaths among women, children and the elderly. The research suggests 3-4% of Gaza’s population was killed violently and notes a substantial number of indirect deaths from the conflict, while stressing that official tallies may be undercounts and that full accounting will take time and significant resources.

via The Guardian|

#casualties #gaza #health-ministry

science7 months ago•6 min saved

Weekend Reads: Unethical vaccine trials, Lancet controversy, and how science learns from its errors

Retraction Watch’s weekend roundup highlights the CDC’s hepatitis B vaccine trial ethics concerns, The Lancet’s stance on a paper with falsified data, and broader discussions on how the scientific community corrects itself, along with a wide array of related retractions, fraud reporting, and publishing integrity stories.

via Retraction Watch|

#lancet #research-fraud #retraction

health8 months ago•7 min saved

Most statin side effects lack evidence, major meta-analysis finds

A Lancet meta-analysis of 19 large randomized trials (over 122,000 participants) finds that most reported statin side effects are not supported by reliable evidence, with real adverse effects being rare (about 1% muscle symptoms; rare rhabdomyolysis; small increases in liver tests and glucose for those near diabetes thresholds). The benefits remain substantial: roughly 25% lower risk of heart attack or stroke and meaningful LDL reductions, with inexpensive generic options (~$40/year). Updated PREVENT-based risk estimates could expand who should start statins, underscoring that fears of side effects should not unduly deter appropriate preventive therapy.

via statnews.com|

#cardiovascular-disease #guidelines #health

health8 months ago•3 min saved

Lancet review finds statins far safer than warnings suggest

A Lancet study reviewing trials of statins (over 120,000 participants) finds side effects are rare and not caused by statins, with minimal liver impact and only rare muscle or blood-sugar issues. The findings support updating patient leaflets, emphasize that statins significantly reduce LDL cholesterol and cardiovascular risk, and reinforce their role in preventing heart attacks and strokes.

via BBC|

#cardiovascular-disease #health #lancet

health8 months ago•2 min saved

Big statin side-effect list largely not caused by the drugs, study finds

A Lancet meta-analysis of 19 randomized trials involving about 124,000 participants over roughly 4.5 years finds that 62 of the 66 side-effects listed for statins have no solid evidence of being caused by the drugs; only four (liver test changes, minor liver abnormalities, urine changes, tissue swelling) have evidence supporting them. Overall, the risk of side-effects is very small and the cardiovascular benefits of statins—reducing heart attacks, strokes and cardiovascular deaths—greatly outweigh harms, prompting calls to update labeling to better reflect the evidence and reassure patients and doctors.

via The Guardian|

#cardiovascular #health #lancet

health8 months ago•4 min saved

New Lancet review reaffirms paracetamol safety in pregnancy, debunking autism claims

A Lancet review of 43 high-quality studies involving hundreds of thousands of pregnancies finds no evidence that paracetamol increases autism, ADHD, or developmental issues, even when accounting for genetics and family environment via sibling analyses, reinforcing that paracetamol remains a safe option for fever or pain during pregnancy when used as directed, and countering Trump-era claims linking it to autism.

via BBC|

#autism #health #lancet

military-technology2 years ago•2 min saved

"Russian Drones Unleash Molten Metal; HIMARS Destroys Rocket System; Ukrainian Drones Intercepted; Kyiv Under Attack; Crimea Sea Drone Strike"

Russian drones equipped with explosive drones called Lancets are reportedly firing slugs of molten metal that can bypass the add-on armor used by Ukrainian troops to protect their vehicles from drone attacks. The drones use explosively formed penetrators (EFPs) that can pierce through certain types of armor, making bolt-on slats and cage armor less effective. The Ukrainians may need to find countermeasures such as composite armor or explosive reactive armor to defend against these EFPs, but these solutions come with their own challenges and limitations.

via Forbes|

#armor-penetration #efps #lancet

health3 years ago•3 min saved

Lancet's Spillover Investigation: Bird Flu Claims Two Lives, Including Toddler

The Lancet has launched a scientific commission to investigate "spillover" events, where dangerous pathogens jump from animals to humans, in an effort to prevent future pandemics. The commission aims to understand the behaviors, environments, and policies that contribute to these events and develop effective risk mitigation strategies. The initiative comes as a two-year-old in Cambodia became the second person to die of bird flu within a week. The commission will assess existing strategies and develop a comprehensive approach to curb spillover events, focusing on both disease prevention and cost-benefit analysis.

via The Telegraph|

#bird-flu #health #lancet