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Radical Pair

All articles tagged with #radical pair

Birds' vision may carry Earth's magnetic field through quantum chemistry in the retina
science9 days ago

Birds' vision may carry Earth's magnetic field through quantum chemistry in the retina

Migrating birds may literally see Earth’s magnetic field as a visual overlay produced by radical-pair reactions in retinal cryptochromes (notably CRY4). This quantum mechanism could alter reaction yields depending on field orientation, potentially guiding navigation by mapping magnetic information onto vision. While birds’ orientation changes with rotated magnetic fields and robin cryptochromes show magnetic sensitivity in vitro, direct evidence in a living bird’s receptor and brain remains unproven. A decisive test would require disabling a specific cryptochrome or electron-transfer step in a migratory bird and showing corresponding changes in magnetic orientation, while also detecting a repeatable Earth-strength signal flowing from retina to brain.

Engineered MagLOV proteins enable in vivo quantum sensing with MRI-like imaging
science7 months ago

Engineered MagLOV proteins enable in vivo quantum sensing with MRI-like imaging

Researchers engineered magneto-sensitive fluorescent proteins (MagLOV) that show optically detected magnetic resonance in living cells at room temperature, with single-cell sensitivity and ~10% ODMR contrast. Through directed evolution, variants with tunable magnetic-field responses were created, supporting multiplexed readout, lock-in detection, and spatial localization of fluorescence using magnetic-field gradients (fluorescence MRI). MagLOV reports are also sensitive to the local spin environment (e.g., gadolinium), enabling in situ sensing of cellular microenvironments. Collectively, this work demonstrates a programmable, endogenously expressible quantum-sensing platform in biology with broad imaging and sensing applications.