Tag

Sleep Spindles

All articles tagged with #sleep spindles

Sleep Waves May Shape Alzheimer’s Course, New Study Finds
science5 days ago

Sleep Waves May Shape Alzheimer’s Course, New Study Finds

A small Neurology study of 60 older adults with mild-to-moderate Alzheimer's found higher cerebrospinal fluid orexin levels linked to faster disease progression over three years, while stronger sleep spindle and slow-wave activity during non-REM sleep appeared to mitigate this effect. Women showed higher orexin levels. The study's limitations—a small sample size and no healthy control group—mean results are preliminary, and more research is needed to see if orexin-targeting therapies could influence Alzheimer's by improving sleep and brain clearance of toxic proteins.

The Link Between Sleep Spindles and PTSD Relief and Memory Boosting
neuroscience3 years ago

The Link Between Sleep Spindles and PTSD Relief and Memory Boosting

Sleep spindles, brief bursts of brain activity during sleep, could potentially help regulate anxiety in people with post-traumatic stress disorder (PTSD). The study involved 45 participants who had all experienced trauma, with about half having moderate symptoms of PTSD, and half having milder symptoms or no symptoms at all. The research found that spindle frequency was higher during the “stress visit” than the control visit and that stress was a contributing factor in spindle-specific sleep rhythm changes. The study suggests that sleep hygiene, electrical brain stimulation, or prescription sleep medications could promote the sleep spindles associated with non-rapid eye movement 2 (NREM2) sleep and potentially benefit patients with stress and anxiety disorders.