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Yellow Card Scheme

All articles tagged with #yellow card scheme

MHRA flags over 150 deaths linked to weight-loss drugs as adverse reports surge
health2 hours ago

MHRA flags over 150 deaths linked to weight-loss drugs as adverse reports surge

The MHRA reports more than 150 deaths linked to GLP-1 weight-loss drugs, based on around 150,000 adverse-reaction reports. Tirzepatide (Mounjaro) accounts for the majority of serious reports and near-100 fatalities; semaglutide (Wegovy) and liraglutide (Saxenda) also appear in the data. Regulators caution that reports do not prove causation and that benefits of GLP-1 medicines generally outweigh risks when used under medical supervision; manufacturers stress ongoing safety monitoring.

MHRA Flags Rare Pancreatitis Risk From GLP-1 Weight-Loss Injectables
health6 months ago

MHRA Flags Rare Pancreatitis Risk From GLP-1 Weight-Loss Injectables

Britain’s MHRA warns that GLP-1 weight‑loss injections (semaglutide, tirzepatide) carry a small risk of pancreatitis. With about 1.6 million users in 2024–25, the Yellow Card scheme has logged 1,143 cases of pancreatitis (acute and chronic) and 17 deaths among GLP-1 users, most in 2025 (807 tirzepatide, 166 semaglutide). Fewer reports exist for liraglutide and dulaglutide. Patients should watch for severe, persistent abdominal pain with nausea and report suspected adverse reactions, while researchers use the Yellow Card Biobank to study genetic risk. Manufacturers reiterate safety and supervised use.