Lilly's Zepbound Outperforms Wegovy in Weight Loss Trial

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Source: Investors | Eli Lilly and Company
Lilly's Zepbound Outperforms Wegovy in Weight Loss Trial
Photo: Investors | Eli Lilly and Company
TL;DR Summary

Eli Lilly's Zepbound (tirzepatide) demonstrated superior weight loss results compared to Wegovy (semaglutide) in the SURMOUNT-5 clinical trial, with participants losing an average of 20.2% of their body weight versus 13.7% for Wegovy. The trial involved adults with obesity or overweight conditions without diabetes, and Zepbound, a dual GIP and GLP-1 receptor agonist, outperformed Wegovy on all primary and secondary endpoints. The safety profile was consistent with previous studies, with gastrointestinal issues being the most common side effects.

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