Tirzepatide may deliver bigger weight loss but greater lean-mass loss vs semaglutide, study suggests

TL;DR Summary
A new study suggests Lilly’s tirzepatide yields more weight loss than Novo Nordisk’s semaglutide, but may also cause greater loss of lean body mass, indicating a potential trade-off in body composition.
- Lilly’s tirzepatide sheds lean muscle harder than Novo’s semaglutide, study suggests Endpoints News
- Novo weight-loss drug may preserve lean body mass better than Lilly's, study finds Reuters
- Novo obesity drug outperforms Lilly’s in preserving lean body mass: study Seeking Alpha
- Real-World Evidence Confirms Oral Semaglutide's Metabolic Potency Medical Dialogues
- Tirzepatide linked to more lean mass loss than semaglutide European Medical Journal
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