A new study suggests Lilly’s tirzepatide yields more weight loss than Novo Nordisk’s semaglutide, but may also cause greater loss of lean body mass, indicating a potential trade-off in body composition.
Individuals with higher genetically estimated lean body mass have a lower risk of developing Alzheimer's disease, according to a study using genetic data from the UK Biobank. The study also found that those with higher lean mass in their arms and legs tend to have better cognitive performance. The research suggests that lean mass may be a potential modifiable protective factor for Alzheimer's disease, although further investigation is needed to understand the underlying mechanisms and implications.
Women with obesity and older women clear alcohol from their systems 52% faster than women of healthy weights and younger women, according to a new study. The rate at which alcohol is eliminated from the bloodstream is largely predicted by lean body mass, with lean liver tissue playing a role in metabolizing alcohol. The study analyzed data from 143 women and found that higher fat-free body mass was associated with a faster alcohol elimination rate. The findings also shed light on alcohol metabolism in women who have undergone weight loss surgery, indicating that surgery-induced reductions in lean body mass can affect alcohol elimination rates.