Panoptes System Uses Decoy Nucleotides to Combat Phages
TL;DR
The Panoptes system in bacteria uses decoy cyclic nucleotides to defend against phages by detecting phage anti-defense proteins like Acb2 that sequester these signaling molecules, thereby activating membrane-disrupting effectors to prevent phage replication.
- The Panoptes system uses decoy cyclic nucleotides to defend against phage Nature
- Bacterial Defense Mechanism Identified Using CRISPR-Cas10-Related System with mCpol and 2TMβ geneonline.com
- Panoptes Deploys Decoy Cyclic Nucleotides Against Phages Bioengineer.org
- A miniature CRISPR–Cas10 enzyme confers immunity by inhibitory signalling Nature
- Phages Use Decoy Cyclic Nucleotides to Evade Bacterial Panoptes Defense System geneonline.com
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