Smoking and Sex Influence Bladder Mutation Patterns and Cancer Risk
TL;DR
The study investigates how sex and smoking influence somatic mutations and clonal expansion in normal human bladder tissue, revealing sex-specific differences in mutation selection and a link between smoking and TERT promoter mutations, which may contribute to bladder cancer risk.
- Sex and smoking bias in the selection of somatic mutations in human bladder Nature
- Sex and Smoking Shape Bladder Mutation Patterns Bioengineer.org
- Smoking and biological sex shape healthy bladder tissue evolution, offering clues to cancer risk EurekAlert!
- Bladder Health and Cancer Risk Modulated by Smoking and Biological Sex Inside Precision Medicine
- How Smoking and Biological Sex Influence Healthy Bladder Tissue Development: New Insights into Cancer Risk Bioengineer.org
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